Hookipa Pharma (HOOK) Stock: Why The Price Surged Today

By Amit Chowdhry ● Feb 16, 2022
  • The stock price of Hookipa Pharma Inc (NASDAQ: HOOK) increased by over 35% pre-market today. This is why it happened.

The stock price of Hookipa Pharma Inc (NASDAQ: HOOK) – a company developing a new class of immunotherapeutics based on its proprietary arenavirus platform – increased by over 35% pre-market today. Investors are responding positively to HOOKIPA Pharma announcing it has entered into an amended and restated collaboration and license agreement with Gilead to advance the development of a novel arenaviral immunotherapy as a component of a potential functional curative regimen for human immunodeficiency virus (HIV).

In April 2018, Gilead had licensed exclusive rights to HOOKIPA’s versatile arenaviral platform to develop immunotherapies for HIV and hepatitis B virus (HBV). And under those terms, the companies agreed to collaborate through a joint research phase, after which time Gilead had rights for further development. Under the amended and restated agreement, HOOKIPA is responsible for advancing the HIV program through the completion of a Phase 1b clinical trial, with funding from Gilead via an upfront payment and equity purchases. At the completion of the Phase 1b trial, Gilead has the exclusive right to assume further development of the program. The HBV portion of the agreement remains unchanged.

Hookipa had earned a one-time $4 million preclinical milestone payment under the original 2018 collaboration and license agreement. And upon signing of the amended agreement, Hookipa will receive a payment of $15 million. Plus Gilead will make a $5 million equity investment in HOOKIPA at a premium to the current market price, and up to an additional $30 million of equity financing that can be drawn at HOOKIPA’s discretion by December 31, 2023.

HOOKIPA’s research collaboration with Gilead to develop a potential functional cure for Hepatitis B virus (HBV) continues to move forward under the original agreement terms. And the project progressed successfully into preclinical development, and Gilead plans to advance the program to the IND-enabling stage in 2022, supporting clinical entry of an alternating two-vector arenaviral therapeutic for the treatment of HBV.


“We are pleased to enter into this amended agreement with Gilead which includes provisions that we believe benefit both parties, and we hope ultimately the HIV community. Gilead is helping to advance our novel arenaviral platform technology, which has the potential to complement Gilead’s overall research strategies for cures of HIV and HBV.”

— Joern Aldag, Chief Executive Officer at HOOKIPA

Disclaimer: This content is intended for informational purposes. Before making any investment, you should do your own analysis.