Andreessen Horowitz announced the launch of its new $2.2 billion Crypto Fund V as the venture capital firm increases its investment in blockchain infrastructure, stablecoins, decentralized finance, and crypto-enabled applications.
The fund was introduced by Chris Dixon, Ali Yahya, Guy Wuollet, and Eddy Lazzarin, who said the crypto industry is entering a phase where long-term infrastructure and practical applications are beginning to demonstrate meaningful adoption beyond speculation.
According to the firm, stablecoins have emerged as one of the clearest indicators of sustained crypto utility, with adoption continuing to grow even during market downturns. The company noted that users are increasingly relying on stablecoins for savings, cross-border payments, and commerce because of the speed and lower costs compared to traditional financial systems.
The announcement also highlighted the growth of blockchain-based capital markets, including perpetual futures, prediction markets, on-chain lending, and tokenized assets. The investors said these systems are contributing to the development of a financial infrastructure that operates continuously, settles transactions nearly instantly, and remains globally accessible through internet connectivity.
The firm pointed to evolving regulatory momentum in the United States, specifically citing the GENIUS Act as an example of policy that could provide clearer definitions and safeguards for the crypto sector while allowing continued innovation.
a16z Crypto also said increasing complexity in software systems and the rapid adoption of AI are making blockchain properties such as transparency, verifiability, decentralization, and open economic participation more important. The company believes these characteristics are becoming foundational for applications in payments, creator platforms, decentralized infrastructure, and AI-driven autonomous systems.
The new fund will focus on startups building products and services designed for everyday crypto adoption, with the firm emphasizing that enduring value in computing platforms is created when infrastructure evolves into widely used consumer and enterprise applications.
KEY QUOTES:
“Crypto cycles tend to follow a pattern. A wave of speculation pulls in attention and capital. Some of it gets wasted. Some of it funds infrastructure that wouldn’t otherwise get built.”
“The founders we’re backing with this $2.2 billion fund are working on the part of the cycle that gets less attention and we believe produces more of the lasting value: turning new infrastructure into products people use every day.”
Chris Dixon, Founder And Managing Partner, a16z Crypto; Ali Yahya, General Partner, a16z Crypto; Guy Wuollet, General Partner, a16z Crypto; Eddy Lazzarin, General Partner, a16z Crypto
