Bunkerhill Health, a San Francisco-based company that builds agentic AI infrastructure for hospitals and health systems, has closed a Series B funding round led by Khosla Ventures, with continued participation from Sequoia Capital, Felicis, Optum Ventures, and Y Combinator. The Series B brings total funding across all rounds to $55 million. The company’s platform, Carebricks, is in production at Cleveland Clinic, the University of Texas Medical Branch (UTMB), and Intermountain Health.
Carebricks is designed to give health systems a single platform to build, deploy, and govern AI agents across clinical, operational, and administrative workflows — without requiring the organization to develop AI infrastructure from scratch. Rather than purchasing point solutions for individual use cases, health systems use Carebricks to turn their own clinical and operational ideas into production-grade AI agents. Use cases in deployment include reviewing cardiology imaging for early signs of heart disease, identifying patients who need follow-up care, navigating prior authorizations, and automating registry management.
At UTMB, more than 20 AI agents built on Carebricks are running simultaneously across the institution. A coronary calcium detection agent running on an FDA-cleared algorithm flagged a patient at imminent risk of a heart attack in its first month of deployment, routing him to cardiology where a triple bypass was performed — an outcome UTMB’s care team credited with saving the patient’s life. A nephrology triage agent prioritizes patients by severity and routes cases appropriately, cutting average specialist wait times by more than 50%. A lung nodule agent identifies incidental CT findings and manages each through to appropriate follow-up, addressing urgent cases 80% faster and doubling guideline-concordant follow-up rates while reducing manual coordinator workload significantly.
The funding will be used to expand the Carebricks platform’s capabilities and to advance the governance, monitoring, and safety infrastructure that health systems require to deploy AI at institutional scale.
KEY QUOTES:
“Medicine has advanced faster than our healthcare system’s ability to operationalize it. Every leading health system has more opportunities to improve patient outcomes than its workforce has capacity to address. We believe AI agents can help them turn more of those ideas into reality.”
Nishith Khandwala, Co-Founder and Chief Executive Officer, Bunkerhill Health
“The bottleneck in healthcare AI was never the technology, it was getting a health system to actually run it. Bunkerhill closed that gap. They made it much, much easier to adopt AI and already have traction inside critical health systems that would take most companies years to earn. That is the unlock the whole industry has been waiting for.”
Vinod Khosla, Founder, Khosla Ventures
“We have more than 20 AI agents live on Carebricks at UTMB, working across clinical care, operations, and administration. We’ve already seen tremendous impact on patient care, and we’re only at the beginning of what becomes possible when a health system can operate with agentic AI at this scale.”
Dr. Peter McCaffrey, Chief AI Officer, University of Texas Medical Branch
