Hippocratic AI (see profile here), a leader in clinically safe generative AI for healthcare, has raised $126 million in Series C funding at a $3.5 billion valuation, bringing its total funding to $404 million. The round was led by Avenir Growth, joined by new and existing investors including CapitalG (Google’s growth fund), General Catalyst, Andreessen Horowitz, Kleiner Perkins, Premji Invest, Universal Health Services (UHS), Cincinnati Children’s Hospital Medical Center, WellSpan Health, John Doerr, and Rick Klausner.
The company plans to use the new capital to drive product development, international expansion, and strategic mergers and acquisitions. Hippocratic AI said the investment will also fuel the continued rollout of its generative AI agents to global healthcare organizations.
In just 15 months since commercialization, the company has established partnerships with more than 50 major health systems, payors, and pharmaceutical clients across six countries. It has built over 1,000 clinical use cases and completed more than 115 million patient interactions with zero safety incidents. Hippocratic AI’s technology is being increasingly adopted as healthcare systems seek to scale operations and enhance patient access through AI-driven solutions safely.
Healthcare executives from institutions such as Cleveland Clinic, Northwestern Medicine, University Hospitals, and Cincinnati Children’s Hospital praised Hippocratic AI’s clinically safe and empathetic approach. The company’s partnerships now span payors representing over half of the top 10 in the U.S. and three of the top eight global pharmaceutical companies.
The Series C funding will accelerate Hippocratic AI’s global reach, expand its customer base, and deepen its investment in the Polaris Safety Constellation Architecture—its proprietary framework for clinical safety and validation. The company also intends to pursue targeted acquisitions to enhance its product suite and scale deployment across healthcare sectors.
Founded with the goal to ensure AI in healthcare adheres to the principle of “do no harm,” Hippocratic AI develops non-diagnostic, patient-facing clinical agents that are not used for prescribing or diagnosis. The company’s growing footprint and safety record have positioned it as one of the fastest-rising enterprises in the healthcare AI sector.
KEY QUOTES:
“At Avenir, we focus on investing in category leaders. After speaking with a significant number of customers prior to investing, we believe Hippocratic AI is leading the agentic healthcare category. Importantly, we found that their relentless focus on safety has earned them the trust of healthcare organizations around the world, becoming the safe choice for executives when choosing AI agents for deployment in healthcare.”
Andrew Sugrue, Co-founder of Avenir Growth
“Hippocratic AI is amongst the fastest growing enterprise healthcare companies we’ve seen in the last few years. Their rapid growth is a testament to the demand for solutions to our industry’s labor and patient access crisis, and the unique capabilities that Hippocratic has brought to market to address those needs.”
Julie Yoo, General Partner at Andreessen Horowitz
“At General Catalyst, our Health Assurance vision centers on enabling a system of care that is more proactive, affordable, and accessible care. We believed in Hippocratic AI and the team since inception, and it is a shining example of this thesis in action. They are applying clinically safe, empathetic generative AI in ways that expand access and dignity in care. Their rapid success reflects both their breakthrough solution and the moral imperative to reimagine how care is delivered.”
Hemant Taneja, CEO of General Catalyst
“Every call our agents make is a patient whose life we have helped to make healthier. What this capital allows us to do is touch more lives and help more people while staying true to our core values of ‘do no harm’ and ‘patients first.’ We truly believe that Generative AI agents can help bring in an era of abundance to healthcare never seen before.”
Munjal Shah, Co-founder and CEO of Hippocratic AI
“Hippocratic AI’s focus on safety, empathy, and clinical alignment makes them a trusted partner as we explore new ways to engage and support our patients and members at scale.”
David Newman, MD, Chief Medical Officer of Virtual Care at Sanford Health
“Hippocratic AI’s focus on safety and scale mirrors our mission to support the care team in providing the highest quality pediatric care to every child who needs it. The AI agents open up new opportunities to support families with warmth and precision, whether in scheduling, chronic condition management, or daily guidance.”
Oliver Rhine, Chief Strategy Officer and President of Cincinnati Children’s Global
“At OhioHealth, safety is the cornerstone of every care decision we make, and we hold our partners to the same standard. Hippocratic AI’s unwavering commitment to clinical safety, combined with their rigorous testing and validation process, gives us the confidence to deploy their agents in ways that truly support patients and clinicians alike.”
Dr. Michael Ezzie, MD, Senior Vice President and President of OhioHealth Physician Group
“The safety information on Anna (the name WellSpan Health gave its Hippocratic AI agent) as our AI care assistant is absolutely terrific. We monitor that all the time along with your team. And every one of our clinical leaders and chief medical officers who’ve reviewed that has been very impressed.”
Roxanna Gapstur, PhD, RN, President and Chief Executive Officer of WellSpan Health
“We see AI as a powerful tool to expand our ability to serve patients without expanding clinician burden. What sets Hippocratic AI apart is its uncompromising commitment to empathy, reliability, and clinical safety.”
Dr. Paul R. Hinchey, MD, MBA, Chief Operating Officer of University Hospitals
“At Advocate Health, we are committed to using AI in partnerships that amplify and enhance human connection rather than replace it. Guided by our robust responsible AI framework, we’re leveraging AI agents to make patient conversations more accessible, empathetic and clinically safe while reducing the administrative burden on our care teams. We value partners that focus on real-world safety and co-development of products, helping us deliver timely, personalized communication that builds trust and supports better patient outcomes.”
Andy Crowder, Chief Digital Officer at Advocate Health
