NFX, a venture capital firm known for its focus on network effects and founder-first investing, announced the close of its fourth fund, NFX Fund IV, totaling $325 million. With over $1.5 billion now under management, NFX is positioned among the most significant early-stage funds globally, continuing its mission to back world-class entrepreneurs in AI, biotech, space, cybersecurity, consumer platforms, and emerging sectors.
Founded by experienced operators and entrepreneurs, the NFX team has collectively built ten companies that have exited for over $10 billion. Since its inception eight years ago, the firm has become a defining player in seed-stage venture capital, investing in only 0.4 percent of companies it reviews. Its selective approach, combined with deep operating expertise and extensive founder resources, has helped make NFX one of the top-performing and most influential early-stage firms in Silicon Valley and Israel.
The firm’s focus remains on identifying founders who demonstrate obsession, creativity, and resilience — individuals who mirror the firm’s entrepreneurial DNA. NFX continues to specialize in pre-seed through Series A investments, typically writing checks ranging from $1.5 million to $5 million. While open to working with founders globally, the firm maintains a strong focus on the Bay Area and Israel, two ecosystems it considers central to innovation.
With Fund IV, NFX is emphasizing its commitment to what it calls a technological “turning point.” The firm sees a dramatic expansion in the surface area of investable opportunities — growing by an estimated tenfold — fueled by rapid advances in artificial intelligence, techbio, space technology, cybersecurity, and other next-generation fields.
Among the themes NFX is tracking for its new fund are:
- AI-first consumer experiences that redefine user engagement.
- Bioplatforms that harness AI for real-world improvements in health and sustainability.
- Non-traditional sectors, such as space and women’s health, that are now emerging as investable frontiers.
- Cybersecurity tools built for AI-native ecosystems.
- AI that enables small businesses to scale operations with enterprise-level efficiency.
- AI agents that fuse human-like labor with intelligent software.
- Longevity technologies with the potential to extend human life beyond 160 years.
- AI products focused equally on retention and innovation.
- AI-driven experiences that are stochastic, creative, and human in spirit — what NFX describes as “software with a soul.”
NFX’s team continues to prioritize long-term partnerships with founders, offering not just capital but hands-on operational support, strategic guidance, and access to one of the strongest networks in venture capital. The firm’s name reflects its foundational belief in network effects — the economic principle responsible for approximately 70 percent of value creation in technology — and remains the core of its investment philosophy.
Through Fund IV, NFX aims to identify the next generation of transformative founders building companies at the intersection of AI, science, and human experience — startups capable of reshaping industries and defining the next era of global innovation.
