Onos Health, a healthcare AI company focused on transforming how health plans manage behavioral health, has raised $6.3 million in an oversubscribed venture round to expand its platform and meet growing demand from major U.S. health insurers. The funding round was co-led by Haystack and Pathlight Ventures, with continued support from early backers Bertelsmann Healthcare Investments and Nebular.
The San Francisco–based startup aims to help payers modernize behavioral health management by replacing slow, manual processes with real-time, data-driven intelligence. Behavioral health needs have surged dramatically since the COVID-19 pandemic, with one in four Americans now seeking mental health support. Meanwhile, health plans face escalating costs and inefficiencies that contribute to an estimated $60 billion in annual waste due to care misalignment and administrative overhead.
Onos Health’s proprietary AI models are trained on extensive behavioral health data to help insurers streamline decision-making and eliminate traditional pain points such as prior authorization. By analyzing payer data in real time, the platform enables health plans to identify optimal care pathways for each member—improving outcomes, reducing delays, and minimizing waste.
Early results from pilot deployments show that health plans using Onos have achieved significant performance improvements, including faster care decisions, higher provider adherence to evidence-based standards, and greater satisfaction across provider networks. These improvements are especially critical for high-intensity services such as substance use treatment and applied behavioral analysis (ABA) therapy for autism.
The company’s advisory board features prominent figures in the healthcare and insurance industries, including executives from Optum Behavioral Health, Kaiser Permanente, and Oscar Health. Their experience is helping guide Onos in building clinically responsible, payer-ready AI tools that align financial and clinical objectives across stakeholders.
With this new funding, Onos Health plans to expand its clinical and data science teams and support a growing number of new and existing payer clients. The company continues to advance its mission of redirecting healthcare dollars toward high-quality, effective care while fostering stronger alignment between providers and insurers.
KEY QUOTES:
“Since the pandemic, behavioral health has become the fastest-growing driver of cost for health plans. Managing that growth while ensuring people get timely, appropriate care is one of the biggest challenges in the industry. What excites me about Onos Health is their clinically aligned, responsible use of AI to help payers and providers truly work together to guide members toward the right support at the right time.”
Martin Rosenzweig, former Chief Medical Officer, Optum Behavioral Health
“In the U.S. health system, patients are too often left behind. Costs keep rising, and health plans are forced to choose between higher premiums or outdated processes that create abrasion between providers and payers — leaving members caught in the middle. We built Onos Health to redirect more dollars back to members, get them on the most effective care pathway, and align payers and providers on the right care for people.”
Akshay Agrawal, CEO and Founder, Onos Health
