Pyx Health, an engagement company focused on healthcare’s most vulnerable and hard-to-reach populations, announced the acquisition of FarmboxRx, a healthcare food company that pioneered fresh fruits and vegetables as a covered health intervention.
This deal was made possible by a $47.5 million investment from S2G Investments in strategic partnership with TT Capital Partners, which first invested in Pyx Health in 2023. The deal combines the companies’ deep domain knowledge in healthcare and food systems to drive innovation at the intersection of two historically siloed sectors.
Pyx Health and FarmboxRx are both mission-driven organizations committed to improving health outcomes for health plans’ most vulnerable populations through personalized, scalable support. And Pyx Health’s mentor-driven care navigation model addresses non-medical drivers of health (NMDOH) like loneliness and other support needs, while FarmboxRx enhances this approach by delivering customized food boxes tailored to specific health conditions and goals.
By integrating nutritional support into care pathways, this combined platform will help address food insecurity – which is the top social barrier identified among Pyx Health members while also enabling health plans to incentivize behaviors such as scheduling preventive visits and completing health assessments.
Trust plays a major role in member behavior. Individuals who feel supported are more likely to engage in preventive care and chronic condition management, reducing the need for costly ER visits. By starting with food, Pyx Health and FarmboxRx are utilizing an accessible and tangible resource to foster deeper healthcare relationships and long-term behavior change.
The companies are already working to integrate their platforms and operations to provide a seamless and expanded offering across health plans and provider networks. And this partnership reflects a broader trend toward personalized, relationship-based engagement models that address health-related social needs, while also underscoring growing recognition of food solutions as powerful drivers of measurable improvements in cost, quality, and access.
Advisors: Brownstein Hyatt Farber Schreck provided legal advice to Pyx Health. And Oppenheimer served as the exclusive financial advisor to Farmbox Direct, Inc. on its sale to Pyx Health.
KEY QUOTES:
“Many health plans have the goal of increasing member engagement to help close care gaps. But to do this, first you have to build trust. That’s where Pyx Health comes in, and bringing FarmboxRx under our umbrella is a catalyst for this by showing our members we care about helping them meet critical needs. Simply put, our food boxes literally help to put food on the table while also opening the door to deeper relationships and healthcare engagement. By utilizing food as an entry point, we can bring everyone together.”
Cindy Jordan, CEO and Co-Founder of Pyx Health
“FarmboxRx exists to address the root causes of health disparities among the populations we serve. Building it has been an immensely personal and passionate journey for my team and me, and to pass it on to a company like Pyx Health, which is equally passionate about meeting people where they are to improve health outcomes, is especially exciting.”
FarmboxRx Founder and CEO Ashley Tyrner-Dolce
“Pyx Health and FarmboxRx are a natural match—both are mission-driven, outcomes-oriented, and laser-focused on advancing health equity through innovation. We’re proud to back this union and help catalyze its next phase of growth. We believe this partnership will set a new bar for how technology and human connection can come together to transform health engagement.”
Dan Ripma, Vice President at S2G
