Stellaromics: Spatial Multi-Omic Profiling Company Closes $25 Million In Funding

By Amit Chowdhry • Nov 20, 2023

Stellaromics – a leading provider of in situ spatial multi-omics technology – recently announced that the company has raised $25 million in a Series A financing round. The Series A funding round included Plaisance Capital Management and a private family office based in Silicon Valley.

Launched last year, the company is developing next-generation spatial technology to accelerate the development of fundamentally novel drug treatments, including for autoimmune diseases, cancer, neuropsychiatric disorders, and infectious diseases.

Along with the funding round, Stellaromics has appointed Todd Dickinson, Ph.D., as President & CEO. Dickinson is a life sciences industry pioneer with over 20 years of experience developing and commercializing disruptive genomics technologies. He was an early scientist of Illumina, and held various technical and commercial executive roles both at Illumina, Bionano Genomics, and most recently as CEO of Cantata Bio (formerly Dovetail Genomics and Arc Bio).

Plus, Ye Fu, Ph.D., has been appointed as CTO. And Fu most recently served as Principal at Plaisance Capital Management, where he was a founding team member at several breakthrough biotech companies and a co-founder of Stellaromics. He is widely published, including first-author articles in Cell and Nature Chemical Biology, with over 18,000 citations. His PhD thesis also opened the field of reversible RNA modifications, which is the foundational work for the 2023 Wolf Prize in Chemistry, one of the most prestigious international chemistry awards.

Stellaromics Scientific Co-Founders are renowned scientists Karl Deisseroth, M.D., Ph.D., and Xiao Wang, Ph.D. And together, they patented the company’s proprietary technology, STARmap (Spatially-resolved Transcript Amplicon Readout mapping), capable of measuring expression levels of thousands of genes within intact tissue at the sub-cellular, single molecule level. More recently, Wang has developed a breakthrough RIBOmap (ribosome-bound mRNA mapping) technology to measure protein synthesis at single-cell and spatial resolution. Stellaromics technology is based on ground-breaking research and innovations as published in Science, Nature, and Cell.

With a clear vision in simplifying and automating the capturing of high-resolution 3D information inside in situ tissue. This latest funding round will be used to fortify the business and establish a new company headquarters to house its growing team of innovators. The company will continue to focus on advancing the development of its revolutionary Plexa products. The alpha version is expected to be available via a Technology Access Program in early 2024.

KEY QUOTES:

“Stellaromics is on a mission to propel biomedical research forward by setting a new standard in in situ spatial analysis. Spatial biology has quickly established itself as one of the most exciting biological technologies of this decade. But today’s approaches remain constrained to two-dimensional tissue profiles, and limited largely to expression of a handful of genes at a single point in time. Our goal is to enable scientists to capture ultra high-resolution, three-dimensional, multi-omic information from thick tissue samples, mapping not only gene expression patterns, but also revealing those genes that are being translated to proteins. By generating a far richer, functional readout of each cell in its native state across a broad range of different samples, from tumors to neurological disease samples, our technology will enable a new level of insight into the mechanisms of disease and how to treat them. With this round of funding, we are entering an exciting growth phase as we expand our team, invest in both innovation and product development, and begin commercialization of what we believe will be a transformative in situ 3D profiling technology.”

– CEO Todd Dickinson, Ph.D.