UNCAGED Innovations (see Pulse 2.0 profile here) has brought Academy Award-winning actor and long-time ethical consumerism advocate Natalie Portman on as a strategic partner, a move that strengthens the company’s efforts to scale its next-generation leather alternative across luxury and fashion markets.
The New York-based biomaterials company, founded by entrepreneur Stephanie Downs and biomaterials scientist Dr. Xiaokun Wang, has created what it calls the world’s first grain-based sustainable leather substitute. The material is designed to match the quality and performance characteristics of traditional leather while significantly reducing its environmental impact. According to the company, its production process emits 95 percent fewer greenhouse gases, uses 89 percent less water, and requires 71 percent less energy than animal-derived leather, positioning the product as a compelling alternative for brands facing increasing pressure to meet sustainability commitments.
The leather industry remains one of the most significant contributors to greenhouse gas emissions, deforestation, and toxic chemical waste. UNCAGED Innovations’ founders believe that biomaterials capable of replicating leather’s performance without its environmental burden can shift the trajectory of luxury manufacturing. Portman’s involvement is expected to expand the company’s reach, especially given her history of supporting animal welfare initiatives and her influence among ethically minded consumers.
The company described the partnership as mission-driven, connecting two dedicated vegans who have built their careers around advancing animal protection and environmental stewardship. The collaboration is designed to broaden awareness among both brands and consumers, encouraging adoption of animal-free materials across fashion, accessories, and other sectors that rely heavily on leather.
Portman’s role will center on advocating for the viability and desirability of sustainable luxury materials, while supporting the company as it scales production and broadens its commercial footprint. Downs said the company views biotechnology and design thinking as key tools in reshaping one of the world’s most resource-intensive industries.
The partnership signals UNCAGED Innovations’ growing momentum as demand for next-generation materials capable of meeting luxury standards without relying on animal products increases. With rising pressure from regulators, investors, and consumers, fashion companies are actively seeking pathways toward lower-impact sourcing, and Portman’s involvement is expected to amplify that shift.
KEY QUOTES:
“UNCAGED is one of the most exciting businesses in the biomaterials space that I have seen. The significant market traction they have gained at such an early stage is proof of the demand for materials that are animal-free, luxurious and sustainable. Stephanie and the team at UNCAGED are redefining the leather industry for the better. As a vegan, I’ve spent years advocating for animals, and teaming up with UNCAGED allows me to amplify that mission. Together, we’re using what we each do best to inspire real change.”
Natalie Portman, Actress And Animal Welfare Advocate
“We’re incredibly excited to have Natalie on board as a strategic partner as her voice and credibility bring powerful momentum to our mission. Consumers and businesses alike are demanding sustainable alternatives and together, this collaboration aims to meet that challenge. The biomaterials industry holds the key to a future where materials are regenerative and not destructive. But we are in a race against time to save our planet and evolve the leather industry. By combining biotechnology with design thinking, we’re accelerating sustainable change without compromising aesthetics or performance.”
Stephanie Downs, CEO And Co-Founder Of Uncaged Innovations
